News - ICAN

Outcomes of coronavirus disease 2019-related hospitalization among people with HIV: historical cohort from the Greater Paris area multicenter hospital data warehouse

8 September 2023

Type 2 diabetes: link between aortic flow and epicardial fat discovered

5 September 2023

How to optimize decision making for defibrillator implantation in hypertrophic cardiomyopathy?

5 September 2023

The SINBAD score, a useful tool for predicting major adverse foot events in diabetic patients?

5 September 2023

Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction

5 September 2023

Albumin infusion reduces ascite occurrence in Child-Pugh B patients treated by Atezolizumab-Bevacizumab for advanced HCC

2 September 2023

Atrio-esophageal fistula: Surgical management

2 September 2023

A proposal from the liver forum for the management of comorbidities in non-alcoholic steatohepatitis therapeutic trials

1 September 2023

Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support

31 August 2023

Improved dyspeptic symptoms of type 1 diabetes adults with gastroparesis on hybrid closed loop system: a case series

30 August 2023

FX06 to rescue SARS-CoV-2-induced acute respiratory distress syndrome: a randomized clinical trial

29 August 2023

Identification of the specific molecular and functional signatures of pre-beta-HDL: relevance to cardiovascular disease

28 August 2023

Diagnosis and management of pulmonary veno-occlusive disease

21 August 2023

The Severity of Congenital Hypothyroidism With Gland-In-Situ Predicts Molecular Yield by Targeted Next-Generation Sequencing

18 August 2023

Prevalence and impact of recreational drug use in patients with acute cardiovascular events

15 August 2023

Circulating Sphingolipids and Glucose Homeostasis: An Update

12 August 2023

Increase in intracellular and extracellular myocardial mass in patients with acromegaly: a cardiac magnetic resonance imaging study

7 August 2023

Clinical phenotypes and outcomes associated with SARS-CoV-2 Omicron variants BA.2, BA.5 and BQ.1.1 in critically ill patients with COVID-19: a prospective, multicenter cohort study

7 August 2023

Early renal recovery after acute kidney injury in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study

2 August 2023

Plasma lipidomic analysis to investigate putative biomarkers of P-glycoprotein activity in healthy volunteers

2 August 2023

Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy

1 August 2023

MYH7 p.(Arg1712Gln) is pathogenic founder variant causing hypertrophic cardiomyopathy with overall relatively delayed onset

1 August 2023

At the dawn of potent therapeutics for fatty liver disease – introducing the miniseries on promising pharmacological targets for NASH

1 August 2023

Use of the SINBAD score as a predicting tool for major adverse foot events in patients with diabetic foot ulcer: A French multicentre study

31 July 2023

Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to nonalcoholic steatohepatitis

28 July 2023

Integrated omics approach for the identification of HDL structure-function relationships in PCSK9-related familial hypercholesterolemia

27 July 2023

Kidney disease in adults with Prader-Willi syndrome: international cohort study and systematic literature review

21 July 2023

[Impact of voxelotor on hemoglobin electrophoretic and chromatographic profiles]

21 July 2023

Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart

21 July 2023

Perceptions of bariatric surgery in patients with type 2 diabetes: data from a self-administered questionnaire

13 July 2023

Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support

12 July 2023

Direct-Acting Antivirals and the Risk of Arrhythmias and Conduction Disorders in Patients with Chronic Hepatitis C: A French Nationwide Cohort Study

12 July 2023

Cholinergic modulation shifts the response of CA1 pyramidal cells to depolarizing ramps via TRPM4 Channels with potential implications for place field firing

5 July 2023

Open Versus Laparoscopic Right Hepatectomy for Hepatocellular Carcinoma Following Sequential TACE-PVE: A Multicentric Comparative Study

3 July 2023

Systemic lupus erythematosus-related acute lung disease

3 July 2023

Is It Time to Put Low-Flow Extracorporeal Carbon Dioxide Removal to REST?

1 July 2023

Why Do So Many Nonalcoholic Steatohepatitis Trials Fail?

28 June 2023

Cytokine profiles in adults with imported malaria

26 June 2023

A multi-society Delphi consensus statement on new fatty liver disease nomenclature

24 June 2023

An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma

21 June 2023

Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study

20 June 2023

Successful advanced hepatocellular carcinoma downstaging with atezolizumab-Bevacizumab and radioembolization before liver transplantation

19 June 2023

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

16 June 2023

The effects of hydrocortisone and yohimbine on human behavior in approach-avoidance conflicts

14 June 2023

Baveno VI and VII criteria are not suitable for screening for large varices or clinically significant portal hypertension in patients with hepatocellular carcinoma

9 June 2023

Veno-Arterial Extracorporeal Membrane Oxygenation for Circulatory Failure in COVID-19 Patients: Insights from the ECMOSARS Registry

6 June 2023

New funding from the Health Data Hub (Bpifrance) for the ANNITIA and CardiHACK projects!

5 June 2023

Identification of natural killer markers associated with fatal outcome in COVID-19 patients

5 June 2023

Venovenous extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: A systematic review and meta-analysis of the literature

2 June 2023

Malignancies in Prader-Willi syndrome: results from a large international cohort and literature review

2 June 2023

Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion

1 June 2023

Temporal Trends in the Use of Computed Tomographic Pulmonary Angiography for Suspected Pulmonary Embolism in the Emergency Department : A Retrospective Analysis

1 June 2023

Ceramide analog C2-cer induces a loss in insulin sensitivity in muscle cells through the salvage/recycling pathway

1 June 2023

Sarcopenic obesity: a new diagnostic method using artificial intelligence

31 May 2023

Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

27 May 2023

Metabolomic profiles of 38 acylcarnitines in major depressive episodes before and after treatment

25 May 2023

How can AI be used to stratify the risk of rare hereditary diseases?

20 May 2023

Autoantibodies Neutralizing Type I IFNs in the Bronchoalveolar Lavage of at Least 10% of Patients During Life-Threatening COVID-19 Pneumonia

20 May 2023

Sudden cardiac death after heart transplantation: a population-based study

19 May 2023

High-Dose Steroids for Nonresolving Acute Respiratory Distress Syndrome in Critically Ill COVID-19 Patients Treated With Dexamethasone: A Multicenter Cohort Study

18 May 2023

Differences in clinical characteristics and outcomes between COVID-19 and influenza in critically ill adult patients: A national database study

16 May 2023

Current challenges and future perspectives in treating patients with NAFLD-related cirrhosis

16 May 2023

Ammonia – an enduring foe – What evaluating whole body ammonia metabolism can teach us about cirrhosis and therapies treating hepatic encephalopathy

12 May 2023

LXR signaling controls homeostatic dendritic cell maturation

12 May 2023

IHU ICAN and MSDAVENIR sign a strategic partnership in medical imaging (ICONIC project)

11 May 2023

The ICONIC project: creation of the 1st atlas of cardiac and hepatic imaging in the general population, including people under the age of 40

10 May 2023

Aortic valve stenosis in familial hypercholesterolaemic: Should we systematically screen?

10 May 2023

Alcohol-related liver disease phenotype impacts survival after an acute variceal bleeding episode

10 May 2023

The daily life of Aude, Advanced Practice Nurse in Diabetes

9 May 2023

Antibiotic stewardship in the ICU: time to shift into overdrive

6 May 2023

Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis

4 May 2023

Expert consensus statement on venovenous extracorporeal membrane oxygenation ECMO for COVID-19 severe ARDS: an international Delphi study

2 May 2023

The short-term prognosis of diabetic foot ulceration is independent of nutritional status at admission

2 May 2023

Evaluation of PXL065 – deuterium-stabilized (R)-pioglitazone in patients with NASH: A phase II randomized placebo-controlled trial (DESTINY-1)

2 May 2023

TIPS prevents further decompensation and improves survival in patients with cirrhosis and portal hypertension in an individual patient data meta-analysis

2 May 2023

Rational combination therapy for NASH: Insights from clinical trials and error

1 May 2023

Implication of the new definition of pulmonary hypertension in patients evaluated for heart transplantation

28 April 2023

Additive Effect of APOE Rare Variants on the Phenotype of Familial Hypercholesterolemia

27 April 2023

Additive Effect of APOE Rare Variants on the Phenotype of Familial Hypercholesterolemia

27 April 2023

Prevalence and clinical relevance of VZV lung detection in intensive care unit: A retrospective cohort study

25 April 2023

Value of aortic volumes assessed by automated segmentation of 3D MRI data in patients with thoracic aortic dilatation: A case-control study

25 April 2023

SARS-CoV-2 variants and mutational patterns: relationship with risk of ventilator-associated pneumonia in critically ill COVID-19 patients in the era of dexamethasone

24 April 2023

Subjective and objective survival prediction in mechanically ventilated critically ill patients: a prospective cohort study

19 April 2023

Heart failure: the UTHop’IA project reinforces therapeutic education during hospitalization

17 April 2023

Care,Innovation

Assessment of Droplet Digital PCR for the Detection and Absolute Quantification of Toxoplasma gondii: A Comparative Retrospective Study

15 April 2023

Clinical Trial Landscape in NASH

12 April 2023

[Evolution of the non-insulin therapeutic strategy in type 2 diabetes]

12 April 2023

High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT, Using a Low Threshold

12 April 2023

A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

10 April 2023

Multiple-site decontamination to prevent acquired infection in patients with veno-venous ECMO support

7 April 2023

Determinants of long-term outcomes in patients with COVID-19 supported with ECMO

5 April 2023

Future Treatment Options and Regimens for Nonalcoholic Fatty Liver Disease

4 April 2023

Veno-Pulmonary Arterial Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Should We Consider Mechanical Support of the Pulmonary Circulation From the Outset?

3 April 2023

Pharmacokinetics/pharmacodynamics of ceftobiprole in patients on extracorporeal membrane oxygenation

1 April 2023

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

1 April 2023

Plasma acetyl-l-carnitine and l-carnitine in major depressive episodes: a case-control study before and after treatment

1 April 2023

Machine learning algorithm improves detection of NASH (NAS-based) and at-risk NASH, a development and validation study

31 March 2023

SEQUOIA-HCM: Launch of an international multicenter study to investigate a potential new therapy for hypertrophic cardiomyopathy

30 March 2023

Usefulness of serum procalcitonin and point-of-care multiplex PCR gastro-intestinal panel in acute diarrhoea or colitis in the emergency department

28 March 2023

Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state

28 March 2023

Clinical features of generalized lipodystrophy in Turkey: A cohort analysis

22 March 2023

Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial

21 March 2023

Setting and Monitoring of Mechanical Ventilation During Venovenous ECMO

21 March 2023

Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)

20 March 2023

Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study

20 March 2023

Epigenetics: induced pluripotent stem cells, a promising cellular model for studying parental imprinting diseases

15 March 2023

Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice

15 March 2023

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

14 March 2023

Extracorporeal membrane oxygenation in adults receiving haematopoietic cell transplantation: an international expert statement

13 March 2023

Practical application of the French two-score heart allocation scheme: Insights from a high-volume heart transplantation centre

11 March 2023

Review of the IHU France alliance white paper

10 March 2023

Effect of flow change on brain injury during an experimental model of differential hypoxaemia in cardiogenic shock supported by extracorporeal membrane oxygenation

10 March 2023

Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study

9 March 2023

Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study

9 March 2023

Critically ill severe hypothyroidism: a retrospective multicenter cohort study

9 March 2023

The Severity of Congenital Hypothyroidism with Gland-in-situ Predicts Molecular Yield by Targeted NGS

8 March 2023

Heart transplantation as salvage treatment of intractable infective endocarditis

3 March 2023

Striking differences in weight gain after cART initiation depending on early or advanced presentation: results from the ANRS CO4 FHDH cohort

2 March 2023

International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe

2 March 2023

Association Between Shock Etiology and 5-Year Outcomes After Venoarterial Extracorporeal Membrane Oxygenation

1 March 2023

Job Strain, Burnout, and Suicidal Ideation in Tenured University Hospital Faculty Staff in France in 2021

1 March 2023

Primary cardiovascular prevention in people with HIV: what’s the score?

1 March 2023

T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4-/-) deficient rats in basal and stress conditions

28 February 2023

Enhancer/gene relationships: Need for more reliable genome-wide reference sets

24 February 2023

Strategies to safely rule out pulmonary embolism in COVID-19 outpatients: a multicenter retrospective study

24 February 2023

A look back at the “AI and megadata in tomorrow’s medical research and practice” conference.

22 February 2023

Stimulation of GHRH Neuron Axon Growth by Leptin and Impact of Nutrition during Suckling in Mice

21 February 2023

Perinatal, metabolic, and reproductive features in PPARG-related lipodystrophy

21 February 2023

Recurrences of Atrial Fibrillation Despite Durable Pulmonary Vein Isolation: The PARTY-PVI Study

20 February 2023

Evaluation of PXL065 – Deuterium-Stabilized (R)-Pioglitazone in NASH Patients: a Phase 2 randomized placebo-controlled trial (DESTINY-1)

18 February 2023

Platelet activation and coronavirus disease 2019 mortality: Insights from coagulopathy, antiplatelet therapy and inflammation

14 February 2023

Management of comatose survivors of out-of-hospital cardiac arrest in Europe: current treatment practice and adherence to guidelines

9 February 2023

Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference

8 February 2023

Clinical impact of successful cardioversion for new-onset atrial fibrillation in critically ill septic patients: A preliminary study

8 February 2023

Quality indicators for post-resuscitation care after out-of-hospital cardiac arrest

4 February 2023

[Respiratory manifestations of Ehlers-Danlos syndromes]

3 February 2023

Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial

1 February 2023

The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes

1 February 2023

Races for Heroes 2023: participate in an innovative project and save lives with the PEGASE project!

1 February 2023

Factors Predicting Statin Initiation During Childhood in Familial Hypercholesterolemia: Importance of Genetic Diagnosis

1 February 2023

Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes

31 January 2023

Extracorporeal membrane oxygenation in COVID-19 associated acute respiratory distress syndrome: A narrative review

31 January 2023

Attend the symposium dedicated to AI and Big Data in medical research and practice (February 10, 2023)

30 January 2023

Portrait of Laetitia, 21 years old and student researcher on dilated cardiomyopathy

30 January 2023

Low-Intensity Pulsed Ultrasound-Mediated Blood-Brain Barrier Opening Increases Anti-Programmed Death-Ligand 1 Delivery and Efficacy in Gl261 Mouse Model

30 January 2023

Capacity of HDL to Efflux Cellular Cholesterol from Lipid-Loaded Macrophages Is Reduced in Patients with Familial Hypercholesterolemia

29 January 2023

One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19-related Acute Respiratory Distress Syndrome

15 January 2023

Portal hypertension and variceal bleeding in patients with liver cancer: Evidence gaps for prevention and management

13 January 2023

Trends in clinical characteristics and outcomes of all critically ill COVID-19 adult patients hospitalized in France between March 2020 and June 2021: a national database study

12 January 2023

Comparative outcomes of extracorporeal membrane oxygenation for COVID-19 delivered in experienced European centres during successive SARS-CoV-2 variant outbreaks (ECMO-SURGES): an international, multicentre, retrospective cohort study

11 January 2023

Non-overweight depressed patients who respond to antidepressant treatment have a higher risk of later metabolic syndrome: findings from the METADAP cohort

11 January 2023

Diagnosis and Management of Hepatic Encephalopathy: The French Recommendations

10 January 2023

Training young cardiologists in adult congenital heart disease should be a priority: Results of a French survey

5 January 2023

Nitric Oxide Synthase activity in major depressive episodes before and after antidepressant treatment: Results of a large case-control treatment study

5 January 2023

In 2023, we continue our commitment! Discover our wishes on video

2 January 2023

Event,Life at ICAN

Impact of Prone Position in COVID-19 Patients on Extracorporeal Membrane Oxygenation

1 January 2023

Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study

1 January 2023

Timing of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

1 January 2023

Cardiac adipose tissue volume assessed by computed tomography is a specific and independent predictor of early mortality and critical illness in COVID-19 in type 2-diabetic patients

31 December 2022

Auto-antibodies against type I IFNs in > 10% of critically ill COVID-19 patients: a prospective multicentre study

31 December 2022

The MAOA rs979605 Genetic Polymorphism Is Differentially Associated with Clinical Improvement Following Antidepressant Treatment between Male and Female Depressed Patients

28 December 2022

Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells

28 December 2022

Impact of the 2018 French two-score allocation scheme on the profile of heart transplantation candidates and recipients: Insights from a high-volume centre

27 December 2022

Burden of cardiovascular disease in a large contemporary cohort of patients with heterozygous familial hypercholesterolemia

25 December 2022

Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction

20 December 2022

ROB’EDUC: artificial intelligence at the service of therapeutic education

19 December 2022

Treatment of obesity: study on the protective mechanisms of omega-3 fatty acids

19 December 2022

A multicentric prospective observational study of diagnosis and prognosis features in ICU mesenteric ischemia: the DIAGOMI study

17 December 2022

Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization

16 December 2022

A diagnostic proposal for sarcopenic obesity in adults based on body composition phenotypes

15 December 2022

Prevalence, characteristics and outcome of cardiac manifestations in critically-ill antiphospholipid syndrome patients

15 December 2022

Targeting the ‘vulnerable’ period – first 3-6 months after an acute heart failure admission – the light gets brighter

15 December 2022

Association between common cardiovascular risk factors and clinical phenotype in patients with hypertrophic cardiomyopathy from the European Society of Cardiology (ESC) EurObservational Research Programme (EORP) Cardiomyopathy/Myocarditis registry

13 December 2022

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

12 December 2022

Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study

12 December 2022

Impacts of a high-fat diet on the metabolic profile and the phenotype of atrial myocardium in mice

9 December 2022

Clinical course of arrhythmogenic right ventricular cardiomyopathy with end-stage heart failure and outcome after heart transplantation

9 December 2022

Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction

9 December 2022

Disruption of GCN2 Pathway Aggravates Vascular and Parenchymal Remodeling During Pulmonary Fibrosis

7 December 2022

Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice

4 December 2022

Liberal or restrictive transfusion for VV ECMO – Authors’ reply

2 December 2022

Human versus Artificial Intelligence-Based Echocardiographic Analysis as a Predictor of Outcomes: An Analysis from the World Alliance Societies of Echocardiography COVID Study

1 December 2022

Early Reversal of Right Ventricular Dysfunction after venovenous ECMO in Patients with COVID-19 Pneumonia

1 December 2022

Could the chylomicron marker apoB48 be of value in the diagnosis of chylous effusions?

1 December 2022

Treatment of portal hypertension in patients with HCC in the era of Baveno VII

30 November 2022

French recommendations on the prevention and treatment of osteoporosis secondary to bariatric surgery

25 November 2022

Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review

25 November 2022

Screening and management of portal hypertension in advanced hepatocellular carcinoma: A French practice survey

23 November 2022

Role of Adipose Tissue microRNAs in the Onset of Metabolic Diseases and Implications in the Context of the DOHaD

22 November 2022

Editorial: Endocrine and metabolic diseases – genetic impact and therapies

21 November 2022

The association of ARRB1 polymorphisms with response to antidepressant treatment in depressed patients

21 November 2022

Genetic counselling and testing in pulmonary arterial hypertension -A consensus statement on behalf of the International Consortium for Genetic Studies in PAH

21 November 2022

Efficacy of plasma exchange in patients with anti-MDA5 rapidly progressive interstitial lung disease

18 November 2022

Updates in the management of respiratory virus infections in ICU patients: revisiting the non-SARS-CoV-2 pathogens

18 November 2022

Hepatic and renal improvements with FXR agonist vonafexor in individuals with suspected fibrotic NASH

18 November 2022

Elevated LDL-cholesterol levels among lean mass hyper-responders on low-carbohydrate ketogenic diets deserve urgent clinical attention and further research

18 November 2022

Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis

18 November 2022

Association of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness

18 November 2022

ATP-binding cassette transporters expression in rats with cirrhosis and hepatic encephalopathy

18 November 2022

Time course, factors related to, and prognostic impact of venoarterial extracorporeal membrane flow in cardiogenic shock

18 November 2022

Intravenous Immunoglobulins Tapering and Withdrawal in Systemic Capillary Leak Syndrome (Clarkson Disease)

18 November 2022

Right Ventricular Injury Increases Mortality in Patients with Acute Respiratory Distress Syndrome on Veno-Venous Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

18 November 2022

‘Involve me and I learn’: an experiential teaching approach to improve dyspnea awareness in medical residents

18 November 2022

A history of variceal bleeding is associated with further bleeding under atezolizumab-bevacizumab in patients with HCC

18 November 2022

What is the status of medical research to combat type 2 diabetes (T2D)?

18 November 2022

World Diabetes Day 2022: How to diagnose and treat type 2 diabetes?

18 November 2022

CAVD project: how to reconstitute in vitro mature contractile heart tissue?

17 November 2022

MetaGenoPolis-INRAE and IHU ICAN accelerate research on microbiota and cardiovascular diseases in France

17 November 2022

Effect of the LDL receptor mutation type on incident major adverse cardiovascular events in familial hypercholesterolaemia

15 November 2022

Lipoatrophic diabetes in familial partial lipodystrophy type 2: From insulin resistance to diabetes

15 November 2022

Cardiovascular Prevention in People Living With HIV: Is There a Rationale to Move Beyond Aspirin?

14 November 2022

Efficacy and Safety of Leriglitazone in Patients With Friedreich Ataxia: A Phase 2 Double-Blind, Randomized Controlled Trial (FRAMES)

1 November 2022

Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

17 October 2022

Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Clinical Consensus Statement of the Acute CardioVascular Care Association (ACVC) and the ESC council of Cardio-Oncology-part 2: acute heart failure, acute myocardial diseases, acute venous thromboembolic diseases, and acute arrhythmias

13 October 2022

EHRA consensus on prevention and management of interference due to medical procedures in patients with cardiac implantable electronic devices

13 October 2022

Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

12 October 2022

Transfusion practice in patients receiving VV ECMO (PROTECMO): a prospective, multicentre, observational study

11 October 2022

Acute right ventricular injury phenotyping in ARDS

11 October 2022

Prognostic factors associated with mortality among patients receiving venovenous extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

10 October 2022

Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent

7 October 2022

TIPS for patients with early HCC: A bridge to liver transplantation

6 October 2022

Role of non-invasive methods in detecting liver impairment in familial Mediterranean fever adult patients with persistent hepatic cytolysis

5 October 2022

Proceedings of the annual meeting of the European Consortium of Lipodystrophies (ECLip) Cambridge, UK, 7-8 April 2022

4 October 2022

State-of-the-art CT and MR imaging and assessment of atherosclerotic carotid artery disease: standardization of scanning protocols and measurements-a consensus document by the European Society of Cardiovascular Radiology (ESCR)

4 October 2022

Inotropes, vasopressors, and mechanical circulatory support for treatment of cardiogenic shock complicating myocardial infarction: a systematic review and network meta-analysis

4 October 2022

What consensus in the diagnosis and management of atrial fibrillation?

4 October 2022

Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques

2 October 2022

Effect of intravenous almitrine on intubation or mortality in patients with COVID-19 acute hypoxemic respiratory failure: A multicentre, randomised, double-blind, placebo-controlled trial

2 October 2022

Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity score

1 October 2022

Heart failure: an increased risk for patients with type 2 diabetes?

30 September 2022

World Heart Day 2022: How to better detect atrial cardiomyopathy to avoid atrial fibrillation?

29 September 2022

Event,Innovation

Bronchoscopy for diagnosis of ventilator-associated pneumonia

28 September 2022

Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study

27 September 2022

Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences-a retrospective observational study

26 September 2022

Apixaban and Valve Thrombosis After Transcatheter Aortic Valve Replacement: The ATLANTIS-4D-CT Randomized Clinical Trial Substudy

26 September 2022

Herpesviridae lung reactivation and infection in patients with severe COVID-19 or influenza virus pneumonia: a comparative study

24 September 2022

Bone health in adults with Prader-Willi syndrome: clinical recommendations based on a multicenter cohort study

23 September 2022

The Cost of Diagnosing and Managing Non-alcoholic Steatohepatitis in Europe and the United States

21 September 2022

Heart failure: launch of the ICARD study, with the inclusion of a 1st patient!

21 September 2022

Familial Hypercholesterolemia Awareness Week 2022

21 September 2022

The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes

19 September 2022

Description and Outcome of Severe Hypoglycemic Encephalopathy in the Intensive Care Unit

15 September 2022

Drosophila CRISPR/Cas9 mutants as tools to analyse cardiac filamin function and pathogenicity of human FLNC variants

15 September 2022

Increased atherosclerotic plaque in AOC3 knock-out in ApoE-/- mice and characterization of AOC3 in atherosclerotic human coronary arteries

13 September 2022

Blood ammonia in patients with chronic liver diseases: A better defined role in clinical practice

12 September 2022

Opportunities for improved clinical trial designs in acute respiratory distress syndrome

10 September 2022

Uncategorized,Publications

Hepatic encephalopathy is not a contraindication to pre-emptive TIPS in high-risk patients with cirrhosis with variceal bleeding

9 September 2022

The Cost of Diagnosing and Managing Non-alcoholic Steatohepatitis in Europe and the United States

7 September 2022

Quantitative magnetic resonance cholangiopancreatography metrics are associated with disease severity and outcomes in people with primary sclerosing cholangitis

3 September 2022

Enhanced recovery in liver transplantation: A value-based approach to complex surgical care, but compliance is missing

1 September 2022

Scleroderma cardiac crisis and scleroderma renal crisis: Two sides of the same coin?

31 August 2022

Stress-Induced Premature Senescence Related to Oxidative Stress in the Developmental Programming of Nonalcoholic Fatty Liver Disease in a Rat Model of Intrauterine Growth Restriction

29 August 2022

Phosphatidylserine improves the anti-inflammatory function of high density lipoproteins (HDL)

22 August 2022

Five-year outcomes in liver transplant patients receiving everolimus with or without a calcineurin inhibitor: Results from the CERTITUDE study

13 August 2022

Association of N-Acetyl Asparagine with QTc in Diabetes: A Metabolomics Study

12 August 2022

Fight against primary liver cancer of metabolic origin: the precious support of the Constance and Andrei Rhoe Foundation

25 July 2022

Patronage,Research

IHU ICAN obtains a €1.5M grant for its Heart & Aorta Atlas!

25 July 2022

Phenotypic Heterogeneity of Fulminant COVID-19–Related Myocarditis in Adults

25 July 2022

Persistence of severe liver fibrosis despite substantial weight loss with bariatric surgery

23 July 2022

Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: Real-life experience from a national reference network

20 July 2022

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases

19 July 2022

Bleeding and thrombotic events in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study

13 July 2022

Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: Real-life experience from a national reference network

11 July 2022

Medtronic reinforces its support for medical research with the IHU ICAN!

6 July 2022

Carbohydrate-restricted diets: what is the link with elevated cholesterol?

6 July 2022

Mechanical circulatory support in the treatment of cardiogenic shock

5 July 2022

Arrhythmogenic right ventricular cardiomyopathy: the never-ending quest for a risk calculator

1 July 2022

Clinico-biological markers for the prognosis of status epilepticus in adults

1 July 2022

Bariatric surgery and human fertility

30 June 2022

Arrhythmogenic right ventricular cardiomyopathy: the never-ending quest for a risk calculator

29 June 2022

Clinico-biological markers for the prognosis of status epilepticus in adults

29 June 2022

Long-term evolution of humoral immune response after SARS-CoV-2 infection

29 June 2022

Comparison of Patients Infected With Delta Versus Omicron COVID-19 Variants Presenting to Paris Emergency Departments : A Retrospective Cohort Study

25 June 2022

Validation of survival prediction models for ECMO in Sars-CoV-2-related acute respiratory distress syndrome

21 June 2022

Heroes’ Run 2022 : our commitment to fighting heart failure

21 June 2022

Event,Life at ICAN

Role of insulin resistance on fertility – Focus on polycystic ovary syndrome

20 June 2022

Endothelial cell biomarkers in critically ill COVID-19 patients with encephalitis

20 June 2022

Drug-associated hyperammonaemia: a Bayesian analysis of the WHO Pharmacovigilance Database

18 June 2022

Impact of diabetes on COVID-19 prognosis beyond comorbidity burden: the CORONADO initiative

15 June 2022

The scaffold-dependent function of RIPK1 in experimental non-alcoholic steatohepatitis

15 June 2022

Exercise and bariatric surgery: A systematic review and meta-analysis of the feasibility and acceptability of exercise and controlled trial methods

13 June 2022

National Foot Health Week 2022: How to prevent diabetic foot wounds?

13 June 2022

Venoarterial extracorporeal membrane oxygenation flow or dobutamine to improve microcirculation during ECMO for refractory cardiogenic shock

11 June 2022

Classical and non-classical congenital adrenal hyperplasia: What is the difference in subsequent fertility?

10 June 2022

Breakthroughs in therapies for NASH and remaining challenges

10 June 2022

International Nash Day 2022: How to fight Non-alcoholic steatohepatitis?

9 June 2022

Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial

9 June 2022

Pre-emptive treatment of West Nile Virus after split liver transplantation

8 June 2022

Association between metabolic disorders and seminal plasma miRNA levels: a pilot study

7 June 2022

Who? When? Where? How? Still the alpha and omega of extracorporeal cardiopulmonary resuscitation

7 June 2022

The critical role of the TB5 domain of Fibrillin-1 in endochondral ossification

4 June 2022

Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes

4 June 2022

Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits

2 June 2022

Impact of chronic coronary syndromes on cardiovascular hospitalization and mortality: The ESC-EORP CICD-LT registry

2 June 2022

Venovenous extracorporeal CO 2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: A systematic review and meta-analysis of the literature

2 June 2022

Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits

2 June 2022

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies

1 June 2022

Somatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations

1 June 2022

It’s Not Just the Prices: Time-Driven Activity-Based Costing for Initiation of Veno-Venous Extracorporeal Membrane Oxygenation at Three International Sites-A Case Review

1 June 2022

Normal HDL cholesterol efflux and anti-inflammatory capacities in type 2 diabetes despite lipidomic abnormalities

1 June 2022

Profound systemic alteration of the immune phenotype and an immunoglobulin switch in Erdheim-Chester disease in 78 patients from a single center

1 June 2022

Comparison of HIV-Infected and Noninfected Patients Undergoing Bariatric Surgery: The ObeVIH Study

1 June 2022

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies

1 June 2022

Somatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations

1 June 2022

Thoracic manifestations of Behcet’s disease

31 May 2022

Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease

26 May 2022

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

24 May 2022

NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia

24 May 2022

The CT-AF study: imaging as a decision support in atrial ablation?

24 May 2022

APOE Molecular Spectrum in a French Cohort with Primary Dyslipidemia

22 May 2022

Direct oral anticoagulant versus low molecular weight heparin for the treatment of cancer-associated venous thromboembolism: 2022 updated systematic review and meta-analysis of randomized controlled trials

21 May 2022

Enhanced recovery after cardiac surgery under CPB or off pump

21 May 2022

The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets

20 May 2022

Plasma fatty acid composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans

19 May 2022

Apixaban vs. standard of care after transcatheter aortic valve implantation: the ATLANTIS trial

18 May 2022

Monocyte: A New Player in the Pathophysiology of Herpes Simplex Virus Reactivation in ICU Patients?

17 May 2022

In-ICU-acquired infections in flare-up systemic rheumatic disease patients receiving immunosuppressant

10 May 2022

Cumulative incidence of SARS-CoV-2 infection and associated risk factors among frontline health care workers in Paris: the SEROCOV cohort study

4 May 2022

Projet CMRAI : Detecting the vulnerable aorta in MRI for precision cardiovascular medicine

26 April 2022

Research,Innovation

Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: Real-life experience from a national reference network

20 April 2022

Lack of Association Between Perioperative Medication and Postoperative Delirium in Hip Fracture Patients in an Orthogeriatric Care Pathway

12 April 2022

April 7, 2022: World Health Day: The IHU model to tackle the public health challenge of cardiometabolic diseases and accelerate medical innovation at the service of the patient.

7 April 2022

Performance evaluation of the fully automated random-access multiparameter Sysmex CN-6000 hemostasis analyzer at a core laboratory with a high sample throughput

6 April 2022

An international survey on patterns of practice in NAFLD and expectations for therapies-The POP-NEXT project

1 April 2022

The Right Ventricle During Veno-Venous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: Can We Protect the Injured Ventricle?

1 April 2022

Extracorporeal Membrane Oxygenation for Respiratory Failure Related to COVID-19: A Nationwide Cohort Study

29 March 2022

Platelet-Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

29 March 2022

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes

28 March 2022

The IHU ICAN participates in the 2022 hero race!

24 March 2022

Launch of the META INF T2D study

24 March 2022

Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia

18 March 2022

Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19

17 March 2022

March 4 – World Obesity Day: Focus on Sarcopenic Obesity (OS)

11 March 2022

Persistence of severe hepatic fibrosis despite substantial weight loss with bariatric surgery

8 March 2022

European Reference Network for rare, low prevalence, or complex diseases of the heart (ERN GUARD-Heart): 5 year anniversary

8 March 2022

Macrophage SR-B1 in atherosclerotic cardiovascular disease

7 March 2022

Electrical Impedance Tomography Monitoring of Bronchoalveolar Lavage in Patients With Acute Respiratory Distress Syndrome

2 March 2022

Suppression of tumorigenicity-2 (ST2) is a promising biomarker in heart transplantation

21 February 2022

Prevalence of familial hypercholesterolaemia in patient presenting with premature acute coronary syndrome

2 February 2022

IHU ICAN creates a new platform entirely dedicated to the processing and analysis of health data: ICAN I/O

26 January 2022

IHU-ICAN participates in Expo Dubai 2020

25 January 2022

Persistence of severe liver fibrosis despite substantial weight loss with bariatric surgery

25 January 2022

Impacts of a high-fat diet on the metabolic profile and phenotype of atrial myocardium in mice

24 January 2022

New Scientific Advisory Board for the IHU

24 January 2022

Awake ECMO for COVID-19 Induced Acute Respiratory Distress Syndrome

19 January 2022

The IHU-ICAN, a key player in cardiometabolic imaging

17 January 2022

Laurence Comte-Arassus joins the IHU-ICAN Board of Directors

17 January 2022

équipes cliniques IHU ICAN

Clinique NASH, an innovative care pathway unique in France

17 January 2022

The MAESTRIA project: Artificial intelligence at the service of innovation

17 January 2022

Successful launch of the XVIVO trial

17 January 2022

Paternally expressed gene 3 (Pw1/Peg3) promotes sexual dimorphism in metabolism and behavior

13 January 2022

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases

8 January 2022

Metabolomics in the understanding and management of hepatic encephalopathy

1 January 2022

Atrial fibrillation and stroke: are we looking in the right direction?

13 December 2021