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News

  • What is an IHU?
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Outcomes of coronavirus disease 2019-related hospitalization among people with HIV: historical cohort from the Greater Paris area multicenter hospital data warehouse

8 September 2023

Publications

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Type 2 diabetes: link between aortic flow and epicardial fat discovered

5 September 2023

Research

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How to optimize decision making for defibrillator implantation in hypertrophic cardiomyopathy?

5 September 2023

Research

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The SINBAD score, a useful tool for predicting major adverse foot events in diabetic patients?

5 September 2023

Research

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Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction

5 September 2023

Publications

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Albumin infusion reduces ascite occurrence in Child-Pugh B patients treated by Atezolizumab-Bevacizumab for advanced HCC

2 September 2023

Publications

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Atrio-esophageal fistula: Surgical management

2 September 2023

Publications

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A proposal from the liver forum for the management of comorbidities in non-alcoholic steatohepatitis therapeutic trials

1 September 2023

Publications

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Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support

31 August 2023

Publications

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Improved dyspeptic symptoms of type 1 diabetes adults with gastroparesis on hybrid closed loop system: a case series

30 August 2023

Publications

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FX06 to rescue SARS-CoV-2-induced acute respiratory distress syndrome: a randomized clinical trial

29 August 2023

Publications

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Identification of the specific molecular and functional signatures of pre-beta-HDL: relevance to cardiovascular disease

28 August 2023

Publications

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Diagnosis and management of pulmonary veno-occlusive disease

21 August 2023

Publications

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The Severity of Congenital Hypothyroidism With Gland-In-Situ Predicts Molecular Yield by Targeted Next-Generation Sequencing

18 August 2023

Publications

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Prevalence and impact of recreational drug use in patients with acute cardiovascular events

15 August 2023

Publications

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Circulating Sphingolipids and Glucose Homeostasis: An Update

12 August 2023

Publications

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Increase in intracellular and extracellular myocardial mass in patients with acromegaly: a cardiac magnetic resonance imaging study

7 August 2023

Publications

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Clinical phenotypes and outcomes associated with SARS-CoV-2 Omicron variants BA.2, BA.5 and BQ.1.1 in critically ill patients with COVID-19: a prospective, multicenter cohort study

7 August 2023

Publications

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Early renal recovery after acute kidney injury in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study

2 August 2023

Publications

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Plasma lipidomic analysis to investigate putative biomarkers of P-glycoprotein activity in healthy volunteers

2 August 2023

Publications

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Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy

1 August 2023

Publications

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MYH7 p.(Arg1712Gln) is pathogenic founder variant causing hypertrophic cardiomyopathy with overall relatively delayed onset

1 August 2023

Publications

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At the dawn of potent therapeutics for fatty liver disease – introducing the miniseries on promising pharmacological targets for NASH

1 August 2023

Publications

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Use of the SINBAD score as a predicting tool for major adverse foot events in patients with diabetic foot ulcer: A French multicentre study

31 July 2023

Publications

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Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to nonalcoholic steatohepatitis

28 July 2023

Publications

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Integrated omics approach for the identification of HDL structure-function relationships in PCSK9-related familial hypercholesterolemia

27 July 2023

Publications

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Kidney disease in adults with Prader-Willi syndrome: international cohort study and systematic literature review

21 July 2023

Publications

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[Impact of voxelotor on hemoglobin electrophoretic and chromatographic profiles]

21 July 2023

Publications

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Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart

21 July 2023

Publications

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Perceptions of bariatric surgery in patients with type 2 diabetes: data from a self-administered questionnaire

13 July 2023

Publications

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Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support

12 July 2023

Publications

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Direct-Acting Antivirals and the Risk of Arrhythmias and Conduction Disorders in Patients with Chronic Hepatitis C: A French Nationwide Cohort Study

12 July 2023

Publications

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Cholinergic modulation shifts the response of CA1 pyramidal cells to depolarizing ramps via TRPM4 Channels with potential implications for place field firing

5 July 2023

Publications

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Open Versus Laparoscopic Right Hepatectomy for Hepatocellular Carcinoma Following Sequential TACE-PVE: A Multicentric Comparative Study

3 July 2023

Publications

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Systemic lupus erythematosus-related acute lung disease

3 July 2023

Publications

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Is It Time to Put Low-Flow Extracorporeal Carbon Dioxide Removal to REST?

1 July 2023

Publications

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Why Do So Many Nonalcoholic Steatohepatitis Trials Fail?

28 June 2023

Publications

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Cytokine profiles in adults with imported malaria

26 June 2023

Publications

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A multi-society Delphi consensus statement on new fatty liver disease nomenclature

24 June 2023

Publications

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An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma

21 June 2023

Publications

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Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study

20 June 2023

Publications

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Successful advanced hepatocellular carcinoma downstaging with atezolizumab-Bevacizumab and radioembolization before liver transplantation

19 June 2023

Publications

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ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

16 June 2023

Publications

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The effects of hydrocortisone and yohimbine on human behavior in approach-avoidance conflicts

14 June 2023

Publications

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Baveno VI and VII criteria are not suitable for screening for large varices or clinically significant portal hypertension in patients with hepatocellular carcinoma

9 June 2023

Publications

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Veno-Arterial Extracorporeal Membrane Oxygenation for Circulatory Failure in COVID-19 Patients: Insights from the ECMOSARS Registry

6 June 2023

Publications

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New funding from the Health Data Hub (Bpifrance) for the ANNITIA and CardiHACK projects!

5 June 2023

Research

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Identification of natural killer markers associated with fatal outcome in COVID-19 patients

5 June 2023

Publications

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Venovenous extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: A systematic review and meta-analysis of the literature

2 June 2023

Publications

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Malignancies in Prader-Willi syndrome: results from a large international cohort and literature review

2 June 2023

Publications

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Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion

1 June 2023

Publications

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Temporal Trends in the Use of Computed Tomographic Pulmonary Angiography for Suspected Pulmonary Embolism in the Emergency Department : A Retrospective Analysis

1 June 2023

Publications

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Ceramide analog C2-cer induces a loss in insulin sensitivity in muscle cells through the salvage/recycling pathway

1 June 2023

Publications

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Sarcopenic obesity: a new diagnostic method using artificial intelligence

31 May 2023

Research

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Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

27 May 2023

Publications

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Metabolomic profiles of 38 acylcarnitines in major depressive episodes before and after treatment

25 May 2023

Publications

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How can AI be used to stratify the risk of rare hereditary diseases?

20 May 2023

Research

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Autoantibodies Neutralizing Type I IFNs in the Bronchoalveolar Lavage of at Least 10% of Patients During Life-Threatening COVID-19 Pneumonia

20 May 2023

Publications

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Sudden cardiac death after heart transplantation: a population-based study

19 May 2023

Publications

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High-Dose Steroids for Nonresolving Acute Respiratory Distress Syndrome in Critically Ill COVID-19 Patients Treated With Dexamethasone: A Multicenter Cohort Study

18 May 2023

Publications

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Differences in clinical characteristics and outcomes between COVID-19 and influenza in critically ill adult patients: A national database study

16 May 2023

Publications

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Current challenges and future perspectives in treating patients with NAFLD-related cirrhosis

16 May 2023

Publications

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Ammonia – an enduring foe – What evaluating whole body ammonia metabolism can teach us about cirrhosis and therapies treating hepatic encephalopathy

12 May 2023

Publications

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LXR signaling controls homeostatic dendritic cell maturation

12 May 2023

Publications

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IHU ICAN and MSDAVENIR sign a strategic partnership in medical imaging (ICONIC project)

11 May 2023

Research

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The ICONIC project: creation of the 1st atlas of cardiac and hepatic imaging in the general population, including people under the age of 40

10 May 2023

Research

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Aortic valve stenosis in familial hypercholesterolaemic: Should we systematically screen?

10 May 2023

Publications

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Alcohol-related liver disease phenotype impacts survival after an acute variceal bleeding episode

10 May 2023

Publications

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The daily life of Aude, Advanced Practice Nurse in Diabetes

9 May 2023

Care

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Antibiotic stewardship in the ICU: time to shift into overdrive

6 May 2023

Publications

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Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis

4 May 2023

Publications

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Expert consensus statement on venovenous extracorporeal membrane oxygenation ECMO for COVID-19 severe ARDS: an international Delphi study

2 May 2023

Publications

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The short-term prognosis of diabetic foot ulceration is independent of nutritional status at admission

2 May 2023

Publications

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Evaluation of PXL065 – deuterium-stabilized (R)-pioglitazone in patients with NASH: A phase II randomized placebo-controlled trial (DESTINY-1)

2 May 2023

Publications

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TIPS prevents further decompensation and improves survival in patients with cirrhosis and portal hypertension in an individual patient data meta-analysis

2 May 2023

Publications

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Rational combination therapy for NASH: Insights from clinical trials and error

1 May 2023

Publications

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Implication of the new definition of pulmonary hypertension in patients evaluated for heart transplantation

28 April 2023

Publications

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Additive Effect of APOE Rare Variants on the Phenotype of Familial Hypercholesterolemia

27 April 2023

Publications

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Additive Effect of APOE Rare Variants on the Phenotype of Familial Hypercholesterolemia

27 April 2023

Publications

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Prevalence and clinical relevance of VZV lung detection in intensive care unit: A retrospective cohort study

25 April 2023

Publications

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Value of aortic volumes assessed by automated segmentation of 3D MRI data in patients with thoracic aortic dilatation: A case-control study

25 April 2023

Publications

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SARS-CoV-2 variants and mutational patterns: relationship with risk of ventilator-associated pneumonia in critically ill COVID-19 patients in the era of dexamethasone

24 April 2023

Publications

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Subjective and objective survival prediction in mechanically ventilated critically ill patients: a prospective cohort study

19 April 2023

Publications

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Heart failure: the UTHop’IA project reinforces therapeutic education during hospitalization

17 April 2023

Care,Innovation

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Assessment of Droplet Digital PCR for the Detection and Absolute Quantification of Toxoplasma gondii: A Comparative Retrospective Study

15 April 2023

Publications

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Clinical Trial Landscape in NASH

12 April 2023

Publications

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[Evolution of the non-insulin therapeutic strategy in type 2 diabetes]

12 April 2023

Publications

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High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT, Using a Low Threshold

12 April 2023

Publications

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A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures

10 April 2023

Publications

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Multiple-site decontamination to prevent acquired infection in patients with veno-venous ECMO support

7 April 2023

Publications

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Determinants of long-term outcomes in patients with COVID-19 supported with ECMO

5 April 2023

Publications

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Future Treatment Options and Regimens for Nonalcoholic Fatty Liver Disease

4 April 2023

Publications

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Veno-Pulmonary Arterial Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Should We Consider Mechanical Support of the Pulmonary Circulation From the Outset?

3 April 2023

Publications

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Pharmacokinetics/pharmacodynamics of ceftobiprole in patients on extracorporeal membrane oxygenation

1 April 2023

Publications

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RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

1 April 2023

Publications

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Plasma acetyl-l-carnitine and l-carnitine in major depressive episodes: a case-control study before and after treatment

1 April 2023

Publications

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Machine learning algorithm improves detection of NASH (NAS-based) and at-risk NASH, a development and validation study

31 March 2023

Publications

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SEQUOIA-HCM: Launch of an international multicenter study to investigate a potential new therapy for hypertrophic cardiomyopathy

30 March 2023

Research

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Usefulness of serum procalcitonin and point-of-care multiplex PCR gastro-intestinal panel in acute diarrhoea or colitis in the emergency department

28 March 2023

Publications

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Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state

28 March 2023

Publications

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Clinical features of generalized lipodystrophy in Turkey: A cohort analysis

22 March 2023

Publications

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Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial

21 March 2023

Publications

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Setting and Monitoring of Mechanical Ventilation During Venovenous ECMO

21 March 2023

Publications

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Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)

20 March 2023

Publications

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Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study

20 March 2023

Publications

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Epigenetics: induced pluripotent stem cells, a promising cellular model for studying parental imprinting diseases

15 March 2023

Research

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Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice

15 March 2023

Publications

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Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

14 March 2023

Publications

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Extracorporeal membrane oxygenation in adults receiving haematopoietic cell transplantation: an international expert statement

13 March 2023

Publications

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Practical application of the French two-score heart allocation scheme: Insights from a high-volume heart transplantation centre

11 March 2023

Publications

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Review of the IHU France alliance white paper

10 March 2023

Life at ICAN

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Effect of flow change on brain injury during an experimental model of differential hypoxaemia in cardiogenic shock supported by extracorporeal membrane oxygenation

10 March 2023

Publications

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Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study

9 March 2023

Publications

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Evaluation of hypercholesterolemia management in at-risk patients by cardiologists in France: a case vignette-based study

9 March 2023

Publications

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Critically ill severe hypothyroidism: a retrospective multicenter cohort study

9 March 2023

Publications

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The Severity of Congenital Hypothyroidism with Gland-in-situ Predicts Molecular Yield by Targeted NGS

8 March 2023

Publications

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Heart transplantation as salvage treatment of intractable infective endocarditis

3 March 2023

Publications

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Striking differences in weight gain after cART initiation depending on early or advanced presentation: results from the ANRS CO4 FHDH cohort

2 March 2023

Publications

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International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe

2 March 2023

Publications

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Association Between Shock Etiology and 5-Year Outcomes After Venoarterial Extracorporeal Membrane Oxygenation

1 March 2023

Publications

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Job Strain, Burnout, and Suicidal Ideation in Tenured University Hospital Faculty Staff in France in 2021

1 March 2023

Publications

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Primary cardiovascular prevention in people with HIV: what’s the score?

1 March 2023

Publications

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T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4-/-) deficient rats in basal and stress conditions

28 February 2023

Publications

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Enhancer/gene relationships: Need for more reliable genome-wide reference sets

24 February 2023

Publications

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Strategies to safely rule out pulmonary embolism in COVID-19 outpatients: a multicenter retrospective study

24 February 2023

Publications

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A look back at the “AI and megadata in tomorrow’s medical research and practice” conference.

22 February 2023

Event

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Stimulation of GHRH Neuron Axon Growth by Leptin and Impact of Nutrition during Suckling in Mice

21 February 2023

Publications

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Perinatal, metabolic, and reproductive features in PPARG-related lipodystrophy

21 February 2023

Publications

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Recurrences of Atrial Fibrillation Despite Durable Pulmonary Vein Isolation: The PARTY-PVI Study

20 February 2023

Publications

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Evaluation of PXL065 – Deuterium-Stabilized (R)-Pioglitazone in NASH Patients: a Phase 2 randomized placebo-controlled trial (DESTINY-1)

18 February 2023

Publications

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Platelet activation and coronavirus disease 2019 mortality: Insights from coagulopathy, antiplatelet therapy and inflammation

14 February 2023

Publications

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Management of comatose survivors of out-of-hospital cardiac arrest in Europe: current treatment practice and adherence to guidelines

9 February 2023

Publications

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Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference

8 February 2023

Publications

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Clinical impact of successful cardioversion for new-onset atrial fibrillation in critically ill septic patients: A preliminary study

8 February 2023

Publications

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Quality indicators for post-resuscitation care after out-of-hospital cardiac arrest

4 February 2023

Publications

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[Respiratory manifestations of Ehlers-Danlos syndromes]

3 February 2023

Publications

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Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial

1 February 2023

Publications

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The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes

1 February 2023

Publications

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Races for Heroes 2023: participate in an innovative project and save lives with the PEGASE project!

1 February 2023

Event

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Factors Predicting Statin Initiation During Childhood in Familial Hypercholesterolemia: Importance of Genetic Diagnosis

1 February 2023

Publications

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Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes

31 January 2023

Publications

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Extracorporeal membrane oxygenation in COVID-19 associated acute respiratory distress syndrome: A narrative review

31 January 2023

Publications

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Attend the symposium dedicated to AI and Big Data in medical research and practice (February 10, 2023)

30 January 2023

Event

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Portrait of Laetitia, 21 years old and student researcher on dilated cardiomyopathy

30 January 2023

Research

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Low-Intensity Pulsed Ultrasound-Mediated Blood-Brain Barrier Opening Increases Anti-Programmed Death-Ligand 1 Delivery and Efficacy in Gl261 Mouse Model

30 January 2023

Publications

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Capacity of HDL to Efflux Cellular Cholesterol from Lipid-Loaded Macrophages Is Reduced in Patients with Familial Hypercholesterolemia

29 January 2023

Publications

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One-Year Mental and Physical Health Assessment in Survivors after Extracorporeal Membrane Oxygenation for COVID-19-related Acute Respiratory Distress Syndrome

15 January 2023

Publications

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Portal hypertension and variceal bleeding in patients with liver cancer: Evidence gaps for prevention and management

13 January 2023

Publications

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Trends in clinical characteristics and outcomes of all critically ill COVID-19 adult patients hospitalized in France between March 2020 and June 2021: a national database study

12 January 2023

Publications

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Comparative outcomes of extracorporeal membrane oxygenation for COVID-19 delivered in experienced European centres during successive SARS-CoV-2 variant outbreaks (ECMO-SURGES): an international, multicentre, retrospective cohort study

11 January 2023

Publications

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Non-overweight depressed patients who respond to antidepressant treatment have a higher risk of later metabolic syndrome: findings from the METADAP cohort

11 January 2023

Publications

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Diagnosis and Management of Hepatic Encephalopathy: The French Recommendations

10 January 2023

Publications

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Training young cardiologists in adult congenital heart disease should be a priority: Results of a French survey

5 January 2023

Publications

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Nitric Oxide Synthase activity in major depressive episodes before and after antidepressant treatment: Results of a large case-control treatment study

5 January 2023

Publications

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In 2023, we continue our commitment! Discover our wishes on video

2 January 2023

Event,Life at ICAN

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Impact of Prone Position in COVID-19 Patients on Extracorporeal Membrane Oxygenation

1 January 2023

Publications

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Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study

1 January 2023

Publications

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Timing of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

1 January 2023

Publications

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Cardiac adipose tissue volume assessed by computed tomography is a specific and independent predictor of early mortality and critical illness in COVID-19 in type 2-diabetic patients

31 December 2022

Publications

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Auto-antibodies against type I IFNs in > 10% of critically ill COVID-19 patients: a prospective multicentre study

31 December 2022

Publications

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The MAOA rs979605 Genetic Polymorphism Is Differentially Associated with Clinical Improvement Following Antidepressant Treatment between Male and Female Depressed Patients

28 December 2022

Publications

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Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells

28 December 2022

Publications

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Impact of the 2018 French two-score allocation scheme on the profile of heart transplantation candidates and recipients: Insights from a high-volume centre

27 December 2022

Publications

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Burden of cardiovascular disease in a large contemporary cohort of patients with heterozygous familial hypercholesterolemia

25 December 2022

Publications

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Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction

20 December 2022

Publications

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ROB’EDUC: artificial intelligence at the service of therapeutic education

19 December 2022

Innovation

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Treatment of obesity: study on the protective mechanisms of omega-3 fatty acids

19 December 2022

Research

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A multicentric prospective observational study of diagnosis and prognosis features in ICU mesenteric ischemia: the DIAGOMI study

17 December 2022

Publications

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Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization

16 December 2022

Publications

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A diagnostic proposal for sarcopenic obesity in adults based on body composition phenotypes

15 December 2022

Publications

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Prevalence, characteristics and outcome of cardiac manifestations in critically-ill antiphospholipid syndrome patients

15 December 2022

Uncategorized

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Targeting the ‘vulnerable’ period – first 3-6 months after an acute heart failure admission – the light gets brighter

15 December 2022

Publications

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Association between common cardiovascular risk factors and clinical phenotype in patients with hypertrophic cardiomyopathy from the European Society of Cardiology (ESC) EurObservational Research Programme (EORP) Cardiomyopathy/Myocarditis registry

13 December 2022

Publications

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Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

12 December 2022

Publications

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Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study

12 December 2022

Publications

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Impacts of a high-fat diet on the metabolic profile and the phenotype of atrial myocardium in mice

9 December 2022

Publications

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Clinical course of arrhythmogenic right ventricular cardiomyopathy with end-stage heart failure and outcome after heart transplantation

9 December 2022

Publications

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Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction

9 December 2022

Publications

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Disruption of GCN2 Pathway Aggravates Vascular and Parenchymal Remodeling During Pulmonary Fibrosis

7 December 2022

Publications

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Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice

4 December 2022

Publications

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Liberal or restrictive transfusion for VV ECMO – Authors’ reply

2 December 2022

Publications

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Human versus Artificial Intelligence-Based Echocardiographic Analysis as a Predictor of Outcomes: An Analysis from the World Alliance Societies of Echocardiography COVID Study

1 December 2022

Publications

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Early Reversal of Right Ventricular Dysfunction after venovenous ECMO in Patients with COVID-19 Pneumonia

1 December 2022

Publications

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Could the chylomicron marker apoB48 be of value in the diagnosis of chylous effusions?

1 December 2022

Publications

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Treatment of portal hypertension in patients with HCC in the era of Baveno VII

30 November 2022

Publications

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French recommendations on the prevention and treatment of osteoporosis secondary to bariatric surgery

25 November 2022

Publications

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Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review

25 November 2022

Publications

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Screening and management of portal hypertension in advanced hepatocellular carcinoma: A French practice survey

23 November 2022

Publications

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Role of Adipose Tissue microRNAs in the Onset of Metabolic Diseases and Implications in the Context of the DOHaD

22 November 2022

Publications

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Editorial: Endocrine and metabolic diseases – genetic impact and therapies

21 November 2022

Publications

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The association of ARRB1 polymorphisms with response to antidepressant treatment in depressed patients

21 November 2022

Publications

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Genetic counselling and testing in pulmonary arterial hypertension -A consensus statement on behalf of the International Consortium for Genetic Studies in PAH

21 November 2022

Publications

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Efficacy of plasma exchange in patients with anti-MDA5 rapidly progressive interstitial lung disease

18 November 2022

Publications

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Updates in the management of respiratory virus infections in ICU patients: revisiting the non-SARS-CoV-2 pathogens

18 November 2022

Publications

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Hepatic and renal improvements with FXR agonist vonafexor in individuals with suspected fibrotic NASH

18 November 2022

Publications

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Elevated LDL-cholesterol levels among lean mass hyper-responders on low-carbohydrate ketogenic diets deserve urgent clinical attention and further research

18 November 2022

Publications

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Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis

18 November 2022

Publications

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Association of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness

18 November 2022

Publications

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ATP-binding cassette transporters expression in rats with cirrhosis and hepatic encephalopathy

18 November 2022

Publications

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Time course, factors related to, and prognostic impact of venoarterial extracorporeal membrane flow in cardiogenic shock

18 November 2022

Publications

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Intravenous Immunoglobulins Tapering and Withdrawal in Systemic Capillary Leak Syndrome (Clarkson Disease)

18 November 2022

Publications

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Right Ventricular Injury Increases Mortality in Patients with Acute Respiratory Distress Syndrome on Veno-Venous Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

18 November 2022

Publications

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‘Involve me and I learn’: an experiential teaching approach to improve dyspnea awareness in medical residents

18 November 2022

Publications

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A history of variceal bleeding is associated with further bleeding under atezolizumab-bevacizumab in patients with HCC

18 November 2022

Publications

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What is the status of medical research to combat type 2 diabetes (T2D)?

18 November 2022

Care,Research

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World Diabetes Day 2022: How to diagnose and treat type 2 diabetes?

18 November 2022

Care

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CAVD project: how to reconstitute in vitro mature contractile heart tissue?

17 November 2022

Research

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MetaGenoPolis-INRAE and IHU ICAN accelerate research on microbiota and cardiovascular diseases in France

17 November 2022

Research

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Effect of the LDL receptor mutation type on incident major adverse cardiovascular events in familial hypercholesterolaemia

15 November 2022

Publications

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Lipoatrophic diabetes in familial partial lipodystrophy type 2: From insulin resistance to diabetes

15 November 2022

Publications

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Cardiovascular Prevention in People Living With HIV: Is There a Rationale to Move Beyond Aspirin?

14 November 2022

Publications

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Efficacy and Safety of Leriglitazone in Patients With Friedreich Ataxia: A Phase 2 Double-Blind, Randomized Controlled Trial (FRAMES)

1 November 2022

Publications

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Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

17 October 2022

Publications

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Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Clinical Consensus Statement of the Acute CardioVascular Care Association (ACVC) and the ESC council of Cardio-Oncology-part 2: acute heart failure, acute myocardial diseases, acute venous thromboembolic diseases, and acute arrhythmias

13 October 2022

Publications

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EHRA consensus on prevention and management of interference due to medical procedures in patients with cardiac implantable electronic devices

13 October 2022

Publications

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Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

12 October 2022

Publications

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Transfusion practice in patients receiving VV ECMO (PROTECMO): a prospective, multicentre, observational study

11 October 2022

Publications

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Acute right ventricular injury phenotyping in ARDS

11 October 2022

Publications

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Prognostic factors associated with mortality among patients receiving venovenous extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis

10 October 2022

Publications

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Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent

7 October 2022

Publications

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TIPS for patients with early HCC: A bridge to liver transplantation

6 October 2022

Publications

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Role of non-invasive methods in detecting liver impairment in familial Mediterranean fever adult patients with persistent hepatic cytolysis

5 October 2022

Publications

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Proceedings of the annual meeting of the European Consortium of Lipodystrophies (ECLip) Cambridge, UK, 7-8 April 2022

4 October 2022

Publications

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State-of-the-art CT and MR imaging and assessment of atherosclerotic carotid artery disease: standardization of scanning protocols and measurements-a consensus document by the European Society of Cardiovascular Radiology (ESCR)

4 October 2022

Publications

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Inotropes, vasopressors, and mechanical circulatory support for treatment of cardiogenic shock complicating myocardial infarction: a systematic review and network meta-analysis

4 October 2022

Publications

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What consensus in the diagnosis and management of atrial fibrillation?

4 October 2022

Care,Research

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Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques

2 October 2022

Publications

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Effect of intravenous almitrine on intubation or mortality in patients with COVID-19 acute hypoxemic respiratory failure: A multicentre, randomised, double-blind, placebo-controlled trial

2 October 2022

Publications

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Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity score

1 October 2022

Publications

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Heart failure: an increased risk for patients with type 2 diabetes?

30 September 2022

Research

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World Heart Day 2022: How to better detect atrial cardiomyopathy to avoid atrial fibrillation?

29 September 2022

Event,Innovation

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Bronchoscopy for diagnosis of ventilator-associated pneumonia

28 September 2022

Publications

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Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study

27 September 2022

Publications

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Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences-a retrospective observational study

26 September 2022

Publications

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Apixaban and Valve Thrombosis After Transcatheter Aortic Valve Replacement: The ATLANTIS-4D-CT Randomized Clinical Trial Substudy

26 September 2022

Publications

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Herpesviridae lung reactivation and infection in patients with severe COVID-19 or influenza virus pneumonia: a comparative study

24 September 2022

Publications

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Bone health in adults with Prader-Willi syndrome: clinical recommendations based on a multicenter cohort study

23 September 2022

Publications

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The Cost of Diagnosing and Managing Non-alcoholic Steatohepatitis in Europe and the United States

21 September 2022

Publications

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Heart failure: launch of the ICARD study, with the inclusion of a 1st patient!

21 September 2022

Research

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Familial Hypercholesterolemia Awareness Week 2022

21 September 2022

Event,Care

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The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes

19 September 2022

Publications

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Description and Outcome of Severe Hypoglycemic Encephalopathy in the Intensive Care Unit

15 September 2022

Publications

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Drosophila CRISPR/Cas9 mutants as tools to analyse cardiac filamin function and pathogenicity of human FLNC variants

15 September 2022

Publications

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Increased atherosclerotic plaque in AOC3 knock-out in ApoE-/- mice and characterization of AOC3 in atherosclerotic human coronary arteries

13 September 2022

Publications

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Blood ammonia in patients with chronic liver diseases: A better defined role in clinical practice

12 September 2022

Publications

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Opportunities for improved clinical trial designs in acute respiratory distress syndrome

10 September 2022

Uncategorized,Publications

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Hepatic encephalopathy is not a contraindication to pre-emptive TIPS in high-risk patients with cirrhosis with variceal bleeding

9 September 2022

Publications

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The Cost of Diagnosing and Managing Non-alcoholic Steatohepatitis in Europe and the United States

7 September 2022

Publications

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Quantitative magnetic resonance cholangiopancreatography metrics are associated with disease severity and outcomes in people with primary sclerosing cholangitis

3 September 2022

Publications

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Enhanced recovery in liver transplantation: A value-based approach to complex surgical care, but compliance is missing

1 September 2022

Publications

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Scleroderma cardiac crisis and scleroderma renal crisis: Two sides of the same coin?

31 August 2022

Publications

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Stress-Induced Premature Senescence Related to Oxidative Stress in the Developmental Programming of Nonalcoholic Fatty Liver Disease in a Rat Model of Intrauterine Growth Restriction

29 August 2022

Publications

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Phosphatidylserine improves the anti-inflammatory function of high density lipoproteins (HDL)

22 August 2022

Research

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Five-year outcomes in liver transplant patients receiving everolimus with or without a calcineurin inhibitor: Results from the CERTITUDE study

13 August 2022

Publications

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Association of N-Acetyl Asparagine with QTc in Diabetes: A Metabolomics Study

12 August 2022

Publications

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Fight against primary liver cancer of metabolic origin: the precious support of the Constance and Andrei Rhoe Foundation

25 July 2022

Patronage,Research

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IHU ICAN obtains a €1.5M grant for its Heart & Aorta Atlas!

25 July 2022

Innovation

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Phenotypic Heterogeneity of Fulminant COVID-19–Related Myocarditis in Adults

25 July 2022

Publications

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Persistence of severe liver fibrosis despite substantial weight loss with bariatric surgery

23 July 2022

Publications

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Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: Real-life experience from a national reference network

20 July 2022

Publications

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European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases

19 July 2022

Publications

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Bleeding and thrombotic events in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study

13 July 2022

Publications

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Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: Real-life experience from a national reference network

11 July 2022

Publications

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Medtronic reinforces its support for medical research with the IHU ICAN!

6 July 2022

Patronage

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Carbohydrate-restricted diets: what is the link with elevated cholesterol?

6 July 2022

Research

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Mechanical circulatory support in the treatment of cardiogenic shock

5 July 2022

Publications

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Arrhythmogenic right ventricular cardiomyopathy: the never-ending quest for a risk calculator

1 July 2022

Publications

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Clinico-biological markers for the prognosis of status epilepticus in adults

1 July 2022

Publications

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Bariatric surgery and human fertility

30 June 2022

Publications

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Arrhythmogenic right ventricular cardiomyopathy: the never-ending quest for a risk calculator

29 June 2022

Publications

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Clinico-biological markers for the prognosis of status epilepticus in adults

29 June 2022

Publications

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Long-term evolution of humoral immune response after SARS-CoV-2 infection

29 June 2022

Publications

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Comparison of Patients Infected With Delta Versus Omicron COVID-19 Variants Presenting to Paris Emergency Departments : A Retrospective Cohort Study

25 June 2022

Publications

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Validation of survival prediction models for ECMO in Sars-CoV-2-related acute respiratory distress syndrome

21 June 2022

Publications

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Heroes’ Run 2022 : our commitment to fighting heart failure

21 June 2022

Event,Life at ICAN

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Role of insulin resistance on fertility – Focus on polycystic ovary syndrome

20 June 2022

Publications

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Endothelial cell biomarkers in critically ill COVID-19 patients with encephalitis

20 June 2022

Publications

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Drug-associated hyperammonaemia: a Bayesian analysis of the WHO Pharmacovigilance Database

18 June 2022

Publications

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Impact of diabetes on COVID-19 prognosis beyond comorbidity burden: the CORONADO initiative

15 June 2022

Publications

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The scaffold-dependent function of RIPK1 in experimental non-alcoholic steatohepatitis

15 June 2022

Publications

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Exercise and bariatric surgery: A systematic review and meta-analysis of the feasibility and acceptability of exercise and controlled trial methods

13 June 2022

Publications

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National Foot Health Week 2022: How to prevent diabetic foot wounds?

13 June 2022

Care,Research

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Venoarterial extracorporeal membrane oxygenation flow or dobutamine to improve microcirculation during ECMO for refractory cardiogenic shock

11 June 2022

Publications

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Classical and non-classical congenital adrenal hyperplasia: What is the difference in subsequent fertility?

10 June 2022

Publications

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Breakthroughs in therapies for NASH and remaining challenges

10 June 2022

Publications

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International Nash Day 2022: How to fight Non-alcoholic steatohepatitis?

9 June 2022

Care

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Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial

9 June 2022

Publications

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Pre-emptive treatment of West Nile Virus after split liver transplantation

8 June 2022

Publications

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Association between metabolic disorders and seminal plasma miRNA levels: a pilot study

7 June 2022

Publications

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Who? When? Where? How? Still the alpha and omega of extracorporeal cardiopulmonary resuscitation

7 June 2022

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The critical role of the TB5 domain of Fibrillin-1 in endochondral ossification

4 June 2022

Publications

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Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes

4 June 2022

Publications

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Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits

2 June 2022

Publications

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Impact of chronic coronary syndromes on cardiovascular hospitalization and mortality: The ESC-EORP CICD-LT registry

2 June 2022

Publications

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Venovenous extracorporeal CO 2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: A systematic review and meta-analysis of the literature

2 June 2022

Publications

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Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits

2 June 2022

Uncategorized

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Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies

1 June 2022

Publications

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Somatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations

1 June 2022

Publications

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It’s Not Just the Prices: Time-Driven Activity-Based Costing for Initiation of Veno-Venous Extracorporeal Membrane Oxygenation at Three International Sites-A Case Review

1 June 2022

Publications

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Normal HDL cholesterol efflux and anti-inflammatory capacities in type 2 diabetes despite lipidomic abnormalities

1 June 2022

Publications

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Profound systemic alteration of the immune phenotype and an immunoglobulin switch in Erdheim-Chester disease in 78 patients from a single center

1 June 2022

Publications

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Comparison of HIV-Infected and Noninfected Patients Undergoing Bariatric Surgery: The ObeVIH Study

1 June 2022

Publications

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Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies

1 June 2022

Publications

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Somatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations

1 June 2022

Publications

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Thoracic manifestations of Behcet’s disease

31 May 2022

Publications

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Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive interstitial lung disease

26 May 2022

Publications

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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

24 May 2022

Publications

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NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia

24 May 2022

Publications

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The CT-AF study: imaging as a decision support in atrial ablation?

24 May 2022

Research

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APOE Molecular Spectrum in a French Cohort with Primary Dyslipidemia

22 May 2022

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Direct oral anticoagulant versus low molecular weight heparin for the treatment of cancer-associated venous thromboembolism: 2022 updated systematic review and meta-analysis of randomized controlled trials

21 May 2022

Publications

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Enhanced recovery after cardiac surgery under CPB or off pump

21 May 2022

Publications

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The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets

20 May 2022

Publications

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Plasma fatty acid composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans

19 May 2022

Publications

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Apixaban vs. standard of care after transcatheter aortic valve implantation: the ATLANTIS trial

18 May 2022

Publications

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Monocyte: A New Player in the Pathophysiology of Herpes Simplex Virus Reactivation in ICU Patients?

17 May 2022

Publications

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In-ICU-acquired infections in flare-up systemic rheumatic disease patients receiving immunosuppressant

10 May 2022

Publications

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Cumulative incidence of SARS-CoV-2 infection and associated risk factors among frontline health care workers in Paris: the SEROCOV cohort study

4 May 2022

Publications

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Projet CMRAI : Detecting the vulnerable aorta in MRI for precision cardiovascular medicine

26 April 2022

Research,Innovation

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Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: Real-life experience from a national reference network

20 April 2022

Publications

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Lack of Association Between Perioperative Medication and Postoperative Delirium in Hip Fracture Patients in an Orthogeriatric Care Pathway

12 April 2022

Publications

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April 7, 2022: World Health Day: The IHU model to tackle the public health challenge of cardiometabolic diseases and accelerate medical innovation at the service of the patient.

7 April 2022

Innovation

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Performance evaluation of the fully automated random-access multiparameter Sysmex CN-6000 hemostasis analyzer at a core laboratory with a high sample throughput

6 April 2022

Publications

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An international survey on patterns of practice in NAFLD and expectations for therapies-The POP-NEXT project

1 April 2022

Publications

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The Right Ventricle During Veno-Venous Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: Can We Protect the Injured Ventricle?

1 April 2022

Publications

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Extracorporeal Membrane Oxygenation for Respiratory Failure Related to COVID-19: A Nationwide Cohort Study

29 March 2022

Publications

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Platelet-Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

29 March 2022

Publications

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Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes

28 March 2022

Publications

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The IHU ICAN participates in the 2022 hero race!

24 March 2022

Event

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Launch of the META INF T2D study

24 March 2022

Research

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Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia

18 March 2022

Publications

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Clinical Interest of Serum Alpha-2 Macroglobulin, Apolipoprotein A1, and Haptoglobin in Patients with Non-Alcoholic Fatty Liver Disease, with and without Type 2 Diabetes, before or during COVID-19

17 March 2022

Publications

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March 4 – World Obesity Day: Focus on Sarcopenic Obesity (OS)

11 March 2022

Research

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Persistence of severe hepatic fibrosis despite substantial weight loss with bariatric surgery

8 March 2022

Research

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European Reference Network for rare, low prevalence, or complex diseases of the heart (ERN GUARD-Heart): 5 year anniversary

8 March 2022

Publications

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Macrophage SR-B1 in atherosclerotic cardiovascular disease

7 March 2022

Publications

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Electrical Impedance Tomography Monitoring of Bronchoalveolar Lavage in Patients With Acute Respiratory Distress Syndrome

2 March 2022

Publications

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Suppression of tumorigenicity-2 (ST2) is a promising biomarker in heart transplantation

21 February 2022

Publications

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Prevalence of familial hypercholesterolaemia in patient presenting with premature acute coronary syndrome

2 February 2022

Publications

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IHU ICAN creates a new platform entirely dedicated to the processing and analysis of health data: ICAN I/O

26 January 2022

Life at ICAN

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IHU-ICAN participates in Expo Dubai 2020

25 January 2022

Event

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Persistence of severe liver fibrosis despite substantial weight loss with bariatric surgery

25 January 2022

Publications

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Impacts of a high-fat diet on the metabolic profile and phenotype of atrial myocardium in mice

24 January 2022

Research

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New Scientific Advisory Board for the IHU

24 January 2022

Life at ICAN

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Awake ECMO for COVID-19 Induced Acute Respiratory Distress Syndrome

19 January 2022

Publications

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The IHU-ICAN, a key player in cardiometabolic imaging

17 January 2022

Research

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Laurence Comte-Arassus joins the IHU-ICAN Board of Directors

17 January 2022

Life at ICAN

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équipes cliniques IHU ICAN

Clinique NASH, an innovative care pathway unique in France

17 January 2022

Care,Care

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The MAESTRIA project: Artificial intelligence at the service of innovation

17 January 2022

Research

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Successful launch of the XVIVO trial

17 January 2022

Innovation

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Paternally expressed gene 3 (Pw1/Peg3) promotes sexual dimorphism in metabolism and behavior

13 January 2022

Publications

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Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases

8 January 2022

Publications

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Metabolomics in the understanding and management of hepatic encephalopathy

1 January 2022

Publications

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Atrial fibrillation and stroke: are we looking in the right direction?

13 December 2021

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