Our platform ICAN I/O - Data sciences

ICAN I/O is a platform of expertise focused on the analysis and integration of multi-omics and clinical data. The platform embraces the evolution of modern technologies and the use of robust algorithms to meet research objectives through a collaborative and holistic approach integrating multi-omics technologies and statistical analysis.

The team includes data managers and a data scientist, all of whom have extensive experience gained from working on national and international projects, in collaboration with leading scientists, physicians and researchers on a wide range of scientific topics.

Thanks to this expertise, the IHU ICAN is positioned as a major international player capable of generating massive healthcare data.

Discover the ICAN I/O charter

Clinical research

Database management and curation

Paper CRF

  • Protocol reading
  • Paper CRF review
  • Paper CRF validation

Create eCRF

  • List of variables
  • Implementation in REDCap
  • CRF test
  • CRF validation
  • Creation of user accounts
  • Go live

Edit Checks

  • Creation and validation of the Data-Validation Plan
  • Development / Test / Validation – Selection of mandatory fields

Extraction

  • Data extraction / Dataset creation

Documentation

  • REDCap User Guide
  • Study entry guide
  • Data-Management Study plan

External data

  • Link to external data

eCRF maintenance and data quality control

  • Troubleshooting
  • New version / Amendment
  • User management
  • Query generation

Monitoring

  • Monitor a fraction of data to be monitored

Statistics

Statistical analysis plan
Descriptive analyses (Tables + Figures)
Multivariate analysis

  • Logisitc/Cox-Regression models
  • Model Validation
  • Sensitivity analysis
  • Multiple-Imputation

Machine-Learning

  • Prognostic variables
  • Outcome predictions / Risk prediction model
  • Model validation
  • Development of Clinical Scores

Omics

Team

Maharajah PONNAIAH, Ph.D

Responsible

m.ponnaiah@ihuican.org
(33) 6 51 71 93 08

Mehdi MENAI, Ph.D

Data Manager

Pauline PAULSTEPHENRAJ, Ph.D

Data Scientist/Data Manager

Rose TCHALA SARE, MS

Apprentice – Bioinformatics

Publications