ICAN Clinical Investigation, an expert clinical investigation platform dedicated to cardiometabolic diseases

Located in the IE3M (Institute of Endocrinology, Metabolic Diseases and Internal Medicine) in the heart of the Pitié-Salpêtrière Hospital site, ICAN Clinical Investigation is a clinical investigation platform dedicated to biomedical research. As experts in cardiometabolic diseases, the ICAN Clinical Investigation teams support academic or industrial sponsors in setting up their clinical projects and contribute to the smooth running of clinical trials, from the feasibility stage and the selection of the center to the closing of the project.

Thanks to its unique location in in Europe’s largest public hospitalICAN Clinical Investigation is the key contact for coordinating the various departments within the Pitié-Salpêtrière Hospital and the Department of Clinical Research and Innovation (DRCI) to carry out innovative academic and industrial clinical research projects.

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ICAN Clinical Investigation in a few figures


doctors in the network
of the IHU-ICAN


ongoing clinical studies


innovative care pathways
put in place


patients included in
clinical studies and cohorts
in 2020


patients received a
innovative therapeutic molecule

The ICAN Clinical Investigation platform, expert at all stages of your study

Feasibility study and sizing of the research project

  • Support for sizing the project: number of patients, number and types of examinations, assessment of human resources needs
  • Legal support in the contracting of studies thanks to the expertise of the Legal and Valorization Pole of the IHU-ICAN
  • Assistance in setting up a project by the Scientific Operations Department of the IHU ICAN

Setting up the study

Optimization of recruitment

  • Telephone pre-screening, verification of inclusion and exclusion criteria
  • Very targeted screening “consultations, HDJ, complete hospitalizations, cohorts…”
  • Assistance to investigators during inclusion and follow-up visit

A dedicated patient and sampling circuit

  • Management and organization of the patient circuit between the different departments
  • Preparation of the roadmap and source documents
  • Samples: monitoring the quality of samples, storage
  • Immediate proximity to the Bio ICAN Biological Resource Center (ISO 9001 and NFS 96-900 certifications)

Data quality and responsiveness

  • Completion of the eCRF within the required deadlines
  • Serious adverse event (SAE) reporting within regulatory deadlines
  • Investigator Workbooks Update

Reporting throughout the study

  • Continuity of inclusions and project monitoring thanks to back-up clinical study technicians
  • Reporting throughout the study to the sponsor
  • Budget tracking and invoicing

Analysis of budgetary needs

  • Accurate cost assessment
  • Negotiation of counterparties

Closing of the study

  • Closure and archiving of documents at the end of the study
  • Query management before database freezes

Invoicing of projects and investigator fees

  • Follow-up of counterparties intended for project leaders
  • Flexibility to use counterparties with a dedicated IHU ICAN investigator account

Our research facilities

  • Electrocardiograph
  • Impedance meter
  • DEXA bone densitometer (to assess metabolic health and bone density)
  • FibroScan® (liver elasticity measurement)
  • Cardiac ultrasound
  • Liver ultrasound
  • Cardiometabolic MRI

The team

  • 1 clinical platform manager
  • 1 assistant clinical platform manager
  • 2 research physicians
  • 1 clinical research nurse
  • 15 clinical research associates and clinical study technicians
  • 1 medical electroradiology technician

Jeanne Haidar

Head of the clinical platform

01 84 82 77 80

ICAN Clinical Investigation

E3M Institute


Pitié-Salpêtrière Hospital
47-83 Hospital Boulevard
75013 Paris

Our main partners


  • Inserm
  • Sorbonne University

Academic partners

  • NFSA
  • French Society of Cardiology
  • European Society of Cardiology

Contract Research Organization (CRO)

  • Covance
  • Health Sciences
  • icon
  • Medpace
  • Parexel
  • PDP
  • PRA
  • Syneos Health

Hospital partnerships

  • Annecy
  • Grenoble
  • Lille
  • Lyons
  • Marseilles
  • Nancy
  • Nantes
  • Poitiers
  • Saint Etienne

Pharmaceutical laboratories

Abbott, Allergan, AMGEN, AstraZeneca, Boehringer Ingelheim, Celgene, Enanta Pharmaceuticals, ENYO Pharma, Galecto Biotech, Galmed Pharmaceuticals, Genetech, GENFIT, Intercept Pharmaceuticals, Inventiva, Ionis Pharmaceuticals, Lilly, Madrigal Pharmaceuticals, MSD, NGM Biopharmaceuticals, Novartis, Novo Nordisk, Regeneron Pharmaceuticals, Roche, Sanofi,

Medical device companies

  • Biotronik
  • Boston Scientific
  • Medtronic

The strengths of ICAN Investigation

Custom made

A single point of contact who supervises your project from feasibility to completion of the study


Solid expertise thanks to highly qualified clinical study technicians in the various medical disciplines


Networking thanks to close links with the various departments of Pitié-Salpêtrière and the Clinical Research and Innovation Department (DRCI)


Adaptation of project resources according to needs and inclusion constraints (respect of deadlines, etc.)


Counterparties are negotiated as fairly as possible and ICAN offers great flexibility in their uses (HR, equipment, congresses, etc.)