Portrait of young researchers: Canelle REYDELLET

Understanding the cellular mechanisms of obesity

Cinnamon REYDELLET

UMRS 1166 – ICAN Postdoctoral researcher in the team: Cellular and systemic lipid metabolism in cardiometabolic diseases – Wilfried Le Goff

Awards received / Distinctions

• 2024: New Francophone Atherosclerosis Society thesis completion grant.
• 2023: Poster Award from the French Association for the Study and Research on Obesity.
• 2022: Oral Communication Award, New Francophone Society for Atherosclerosis.
• 2021: Scholarship from the Ministry of Higher Education and Research.

Training

• After earning a bachelor's degree in biology and life sciences, Canelle went on to pursue a master's degree in nutrition and food science at the University of Bordeaux, aware of the impact of nutrition on human health.
• Being very curious by nature, it was during this master's degree that she discovered laboratory research. She then continued her academic studies by writing a thesis on cardio-metabolic diseases, particularly obesity.
• For Canelle, understanding the various cellular factors and mechanisms that can contribute to the development or regression of a disease is a key issue for human health and a real source of motivation.

Research project

• Canelle's main research project focuses on obesity. The work carried out by her team has highlighted the contribution of the ATP-binding cassette G1 (ABCG1) membrane transporter in the formation of fat mass, and more specifically in the storage of lipids within adipocytes, which are key cells in adipose tissue.
• Canelle therefore sought to characterize the role of ABCG1 in adipocytes in greater depth and to study the consequences of its invalidation on the functionality of adipose tissue.
• The various areas of research developed within his team also give him the opportunity to explore other hypotheses in a range of pathophysiological contexts, including dyslipidemia, type 2 diabetes, and hepatic steatosis.